DNA Cardiovascular Disease (ApoE) Test

Discover your risk of experiencing a heart attack, and identify the optimal treatment option for you with a genetic test.


DNA Tests
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* All kits are dispatched within 24 hours. Price includes all laboratory fees and results documents.

About this test

The APOE gene plays a role in determining not only your susceptibility to a heart attack but also the most effective approach for reducing cholesterol levels. Explore your risk and find the best treatment option for you.
  • This test examines various variants of the APOE gene, including:
  • The e2 allele, which is associated with an increased risk of hyperlipoproteinemia type III.
  • The e4 allele, which is linked to high LDL-cholesterol levels and an increased risk of heart disease.
  • Discover the most efficient methods to enhance your heart health based on your genetic profile.


Cardiovascular diseases (CVD), including heart attacks and strokes, can often be prevented by maintaining healthy cholesterol levels.

LDL-cholesterol, commonly referred to as “bad” cholesterol, can accumulate within the walls of blood vessels, resulting in blockages and scarring known as atherosclerosis. Elevated levels of LDL-cholesterol increase the risk of developing CVD.

In addition to elevated LDL-cholesterol levels, increased triglycerides (the primary form of storage fat in the body) and high levels of other low-density lipoproteins, such as beta-very low-density lipoproteins, also contribute to the development of CVD.

Hyperlipoproteinemia type III, a condition characterized by elevated triglycerides and beta-very low-density lipoproteins, is associated with an early onset of peripheral vascular disease and CVD.

Technical Info

The APOE gene is a significant genetic factor in the development of cardiovascular disease (CVD). It also influences how you respond to dietary changes and medications aimed at lowering blood pressure and managing cholesterol levels. This gene encodes Apolipoprotein E (ApoE), a protein critical in cholesterol production, transportation, and utilization within the body. You can determine your APOE genotype with a simple mouth swab test.

The APOE genotype plays a role in assessing an individual’s susceptibility to cardiovascular disease:

  • Two copies of the e3 allele: Not at an increased risk of CVD.
  • One e3 allele and one e2 allele: Not at an increased risk of CVD.
  • Two copies of the e2 allele: Lower LDL-cholesterol levels but an increased risk of hyperlipoproteinemia type III, which can contribute to CVD.
  • One or two copies of the e4 allele: Elevated LDL-cholesterol levels and an increased risk of CVD.

100% Confidentiality

As our client, your privacy is extremely important to us, and we hold all information provided us in strict confidentiality. We will never sell, resell or make available your personal, or financial information to other companies or organizations. You will only be contacted using the method you choose, to confirm your order or to discuss your case. All communication is in the strictest confidence, and for that reason, we require you to create a password that will restrict access to your case. In addition, our privacy policies that have been established in our laboratory and offices safeguard the security of your case.

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